KEGG   Mus musculus (house mouse): 20779
Entry
20779             CDS       T01002                                 
Symbol
Src, pp60c-src
Name
(RefSeq) Rous sarcoma oncogene
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu01521  EGFR tyrosine kinase inhibitor resistance
mmu01522  Endocrine resistance
mmu04012  ErbB signaling pathway
mmu04015  Rap1 signaling pathway
mmu04062  Chemokine signaling pathway
mmu04137  Mitophagy - animal
mmu04144  Endocytosis
mmu04360  Axon guidance
mmu04370  VEGF signaling pathway
mmu04510  Focal adhesion
mmu04520  Adherens junction
mmu04530  Tight junction
mmu04540  Gap junction
mmu04611  Platelet activation
mmu04613  Neutrophil extracellular trap formation
mmu04625  C-type lectin receptor signaling pathway
mmu04727  GABAergic synapse
mmu04750  Inflammatory mediator regulation of TRP channels
mmu04810  Regulation of actin cytoskeleton
mmu04912  GnRH signaling pathway
mmu04915  Estrogen signaling pathway
mmu04917  Prolactin signaling pathway
mmu04919  Thyroid hormone signaling pathway
mmu04921  Oxytocin signaling pathway
mmu04926  Relaxin signaling pathway
mmu05100  Bacterial invasion of epithelial cells
mmu05135  Yersinia infection
mmu05152  Tuberculosis
mmu05161  Hepatitis B
mmu05163  Human cytomegalovirus infection
mmu05167  Kaposi sarcoma-associated herpesvirus infection
mmu05168  Herpes simplex virus 1 infection
mmu05203  Viral carcinogenesis
mmu05205  Proteoglycans in cancer
mmu05207  Chemical carcinogenesis - receptor activation
mmu05208  Chemical carcinogenesis - reactive oxygen species
mmu05219  Bladder cancer
mmu05417  Lipid and atherosclerosis
mmu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    20779 (Src)
   04015 Rap1 signaling pathway
    20779 (Src)
   04370 VEGF signaling pathway
    20779 (Src)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    20779 (Src)
   04137 Mitophagy - animal
    20779 (Src)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    20779 (Src)
   04520 Adherens junction
    20779 (Src)
   04530 Tight junction
    20779 (Src)
   04540 Gap junction
    20779 (Src)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    20779 (Src)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    20779 (Src)
   04613 Neutrophil extracellular trap formation
    20779 (Src)
   04625 C-type lectin receptor signaling pathway
    20779 (Src)
   04062 Chemokine signaling pathway
    20779 (Src)
  09152 Endocrine system
   04912 GnRH signaling pathway
    20779 (Src)
   04915 Estrogen signaling pathway
    20779 (Src)
   04917 Prolactin signaling pathway
    20779 (Src)
   04921 Oxytocin signaling pathway
    20779 (Src)
   04926 Relaxin signaling pathway
    20779 (Src)
   04919 Thyroid hormone signaling pathway
    20779 (Src)
  09156 Nervous system
   04727 GABAergic synapse
    20779 (Src)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    20779 (Src)
  09158 Development and regeneration
   04360 Axon guidance
    20779 (Src)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    20779 (Src)
   05207 Chemical carcinogenesis - receptor activation
    20779 (Src)
   05208 Chemical carcinogenesis - reactive oxygen species
    20779 (Src)
   05203 Viral carcinogenesis
    20779 (Src)
  09162 Cancer: specific types
   05219 Bladder cancer
    20779 (Src)
  09172 Infectious disease: viral
   05161 Hepatitis B
    20779 (Src)
   05168 Herpes simplex virus 1 infection
    20779 (Src)
   05163 Human cytomegalovirus infection
    20779 (Src)
   05167 Kaposi sarcoma-associated herpesvirus infection
    20779 (Src)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    20779 (Src)
   05152 Tuberculosis
    20779 (Src)
   05100 Bacterial invasion of epithelial cells
    20779 (Src)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    20779 (Src)
   05418 Fluid shear stress and atherosclerosis
    20779 (Src)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    20779 (Src)
   01522 Endocrine resistance
    20779 (Src)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    20779 (Src)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    20779 (Src)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     20779 (Src)
Protein kinases [BR:mmu01001]
 Non-receptor tyrosine kinases
  SRC family
   20779 (Src)
Membrane trafficking [BR:mmu04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    20779 (Src)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    20779 (Src)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    20779 (Src)
  Macropinocytosis
   Kinases
    20779 (Src)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH3_10 ABC1 Haspin_kinase SH3_3
Other DBs
NCBI-GeneID: 20779
NCBI-ProteinID: NP_001020566
MGI: 98397
Ensembl: ENSMUSG00000027646
UniProt: P05480
Structure
Position
2:157265828..157313758
AA seq 535 aa
MGSNKSKPKDASQRRRSLEPSENVHGAGGAFPASQTPSKPASADGHRGPSAAFVPPAAEP
KLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDW
WLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESE
TTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLC
HRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLK
PGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYL
RLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTA
RQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERG
YRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
NT seq 1608 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccaaggacgccagccagcggcgccgcagcctggagccc
tcggaaaacgtgcacggggcagggggcgccttcccggcctcacagacaccgagcaagccc
gcctccgccgacggccaccgcgggcccagcgccgccttcgtgccgcccgcggccgagccc
aagctcttcggaggcttcaactcctcggacaccgtcacctccccgcagagggcggggcct
ctggcaggtggggtgaccacctttgtggccctctatgactatgagtcacggacagagact
gacctgtccttcaagaaaggggagcggctgcagattgtcaataacacagagggagactgg
tggctggcacactcgctgagcacgggacagaccggttacatccccagcaactatgtggcg
ccctccgactccatccaggctgaggagtggtactttggcaagatcactagacgggaatca
gagcggctgctgctcaacgccgagaacccgagagggaccttcctcgtgagggagagtgag
accacaaaaggtgcctactgcctctctgtatccgacttcgacaatgccaagggcctaaat
gtgaaacactacaagatccgcaagctggacagcggcggtttctacatcacctcccgcacc
cagttcaacagcctgcagcagctcgtggcttactactccaaacatgctgatggcctgtgt
caccgcctcactaccgtatgtcccacatccaagcctcagacccagggattggccaaggat
gcgtgggagatcccccgggagtccctgcggctggaggtcaagctgggccagggttgcttc
ggagaggtgtggatggggacctggaacggcaccacgagggttgccatcaaaactctgaag
ccaggcaccatgtccccagaggccttcctgcaggaggcccaagtcatgaagaaactgagg
cacgagaaactggtgcagctgtatgctgtggtgtcggaagaacccatttacattgtgaca
gagtacatgaacaaggggagtctgctggactttctcaagggggaaacgggcaaatatttg
cggctaccccagctggtggacatgtctgctcagatcgcttcaggcatggcctatgtggag
cggatgaactatgtgcaccgggaccttcgagccgccaatatcctagtaggggagaacctg
gtgtgcaaagtggccgactttgggttggcccggctcatagaagacaacgaatacacagcc
cggcaaggtgccaaattccccatcaagtggaccgcccctgaagctgctctgtacggcagg
ttcaccatcaagtcggatgtgtggtcctttgggattctgctgaccgagctcaccactaag
ggaagagtgccctatcctgggatggtgaaccgtgaggttctggaccaggtggagcggggc
taccggatgccttgtccccccgagtgccccgagtccctgcatgaccttatgtgccagtgc
tggcggaaggagcccgaggagcggcccaccttcgagtacctgcaggccttcctggaagac
tactttacgtccactgagccacagtaccagcccggggagaacctatag

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (39)   
   KEGG PATHWAY (39)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (26)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (24)   
DNA sequence (52)   
   RefSeq(nuc) (24)   
   GenBank (14)   
   EMBL (14)   
3D Structure (1)   
   PDB (1)   
Protein domain (10)   
   Pfam (10)   
All databases (144)   

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